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History of anthrax—anthrax as a zoonotic disease
Anthrax is not a new disease. It has been known to man for hundreds of years, mostly as an animal disease, typically in agricultural areas. The bacterial life cycle includes spores: this state is responsible for the bacterium’s resilience and enables its dispersal.
Spores—hardcore hibernation

Anthrax does not pass from one animal to another!

The spore stage of anthrax is responsible for its survival in many environments for many years. In most cases, animal contamination occurs from eating or drinking water that contains spores of the bacterium.

Spores ingested by herbivores germinate within the host to produce the vegetative forms; these multiply and express their virulence factors, killing the host. The vegetative form is square-ended and capsulated. Sporulating cells carry elliptic, centrally located spores. Bacilli shed by the dying or dead animal will sporulate on contact with air. Sporulation requires the presence of free oxygen, and the efficiency of the process is influenced by the environmental conditions. The proportion of cells that reach the ultimate stage, a dormant spore, is variable.

Expand your knowledge at the following websites:

SEM Images of Vegetative and Spore Stages(Website 37):


Scanning electron micrograph of Bacillus anthracis

Description: Scanning electron micrograph of Bacillus anthracis spore and vegetative stages. B. anthracis is a Gram-positive, encapsulated, spore-forming, zoonotic, rod prokaryote. Magnification: x700.

link to    Bacillus anthracis

The disease does not spread from animal to animal.

link to Mock and Fouet, 2001

Sceme

 

In agricultural areas, it is customary to vaccinate farm animals annually. An anti-anthrax vaccine has existed for animals since the 1930s. The vaccine compound given to cows contains weakened live spores. The spore buds in the animal’s body and is capable of producing the three toxins, but not the bacterial envelope. This prevents the phagocytotic process, which prevents the bacteria from proliferating. Thus, the toxins produced by the bacteria are not present in amounts capable of causing the disease.

To expand your knowledge, visit the following websites:

About the history of developing vaccines for farm animals against anthrax

8    Wanted, an Anthrax vaccine: Dead or Alive?

8    Epidimiologic Response to Anthrax Outbreaks

 

The worldwide spread of anthrax

Anthrax in animals is hyperendemic or endemic in the following areas of the world: most areas of the Middle East, most areas of equatorial Africa, Mexico, Central Africa, Chile, Argentina, Peru, Bolivia, certain Southeast Asian countries (e.g. Burma (Myanmar), Vietnam, Cambodia, Thailand), Papua New Guinea, China, and some Mediterranean countries. In most of the rest of the world, anthrax occurs only sporadically. In the United States, outbreaks in animals have occurred since 1990 in the Midwest (Kansas, Nebraska, North Dakota, South Dakota, Missouri); in the West (California, Nevada), and in Texas and Oklahoma. In the US, the microorganism remains endemic in the soils of Texas, Oklahoma, and the lower Mississippi valley.

The spread of anthrax—map:

8    World anthrax data site

For more information on anthrax in farm animals:

linkto Anthrax is a biological weapon, 2002

linkto Anthrax in animals Hugh Millar, Attwood January 2003 AG0802

If you want to know more about Bacillus anthracis go to:
i Meeting the culprit  
i History of anthrax—anthrax as a zoonotic disease
i The way that anthrax infects humans- advanced activity
i How is anthrax used as a terrorist weapon?
i Anthrax naturally occurring in humans
i How do we deal with the dangers of anthrax terrorist attacks?
The hope- Pathogenomics approach
What causes a disease?
defendagainst diseasesimmunesystem
Treatment
The hope
ICT project
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